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Zuno-SR (aceclofenac + paracetamol + serratiopeptidase) is a modern formulation, but its ingredients have decades of medical history:
- Paracetamol – 145+ years
- Serratiopeptidase – ~60 years
- Aceclofenac – ~30 years
Together, they form a widely used combination for pain, inflammation, and swelling.
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Price: ৳ 1,960
MRP:
৳
2000
2%
Off
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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Derivative of diclofenac, created to provide similar pain-relieving and anti-inflammatory benefits but with better gastrointestinal tolerability.
proteolytic enzyme originally isolated from Serratia marcescens bacteria in the intestine of silkworms.
History of Zuno-SR (by components)
1. Aceclofenac
Developed: Early 1990s
Origin: A derivative of diclofenac, created to provide similar pain-relieving and anti-inflammatory benefits but with better gastrointestinal tolerability.
Purpose: Designed as a safer NSAID alternative for long-term use in arthritis.
Approval: Became widely used in Europe and Asia for conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
2. Paracetamol (Acetaminophen)
Discovered: 1877
Introduced to medicine: 1950s
Origin: Derived from earlier analgesics (acetanilide, phenacetin).
Reason for popularity:
Effective for pain and fever
Safer than aspirin for the stomach
Current status: One of the most widely used painkillers worldwide.
3. Serratiopeptidase (Serrapeptase)
Discovered: 1960s in Japan
Source: A proteolytic enzyme originally isolated from Serratia marcescens bacteria in the intestine of silkworms.
Purpose:
Reduces inflammation
Helps break down inflammatory proteins
Reduces swelling and promotes healing
Widely used in India, Japan, and parts of Europe for postoperative swelling and musculoskeletal inflammation.
History of Combining These Three Ingredients
By the early 2000s, pharmaceutical companies began combining:
NSAID (aceclofenac)
Analgesic/antipyretic (paracetamol)
Anti-inflammatory enzyme (serratiopeptidase)
Purpose: create a multi-mechanism pain reliever for faster relief in:
muscle pain
joint pain
post-injury swelling
postoperative inflammation
Sustained-release (SR) versions like Zuno-SR came later to provide longer-lasting pain control with fewer doses.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Description: ZUNO-SR
Aceclofenac + Paracetamol + Serratiopeptidase is a combination therapy used to relieve pain and inflammation caused by bone or soft-tissue injuries, as well as to reduce postoperative swelling (oedema) and discomfort. It is effective for both short-term (acute) pain and long-lasting (chronic) pain conditions.
This medication blends aceclofenac, paracetamol, and serratiopeptidase. Together, they help reduce pain and swelling by inhibiting the cyclo-oxygenase (COX) enzyme, which triggers inflammation at sites of injury.
Most side effects are mild and tend to resolve on their own. Common reactions include nausea, vomiting, indigestion, and stomach pain. Seek medical advice if these symptoms persist or worsen.
Take the tablets whole with water, with or without food. Do not chew or crush the tablet. The dosage and duration will be determined by your doctor based on your condition.
Avoid this medicine if you are allergic to NSAIDs such as aspirin, ibuprofen, naproxen, or diclofenac. Do not discontinue treatment without medical guidance. It is not recommended for children, and you should not exceed the prescribed dose or duration. If you are pregnant or breastfeeding, consult your doctor before taking this medication.
✔️ Side Effects
- Nausea
- Stomach Pain
- Loss of appetite
- Diarrhoea
- Stomach upset
- Indigestion
✔️ Interaction
Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), and blood clotting agents (warfarin) should not be taken with Aceclofenac+paracetamol+serratiopeptidase as they may interact.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: Inform your doctor if you have a peptic ulcer, gastric bleeding, severe heart failure, or high blood pressure before taking Aceclofenac+paracetamol+serratiopeptidase.
✔️ Avoid this medicine if you:
- Are allergic to NSAIDs or painkillers (e.g., aspirin, ibuprofen, diclofenac)
- Have a history of heart failure
- Have kidney or liver disease
- Have stomach ulcers or gastrointestinal bleeding
✔️ Storage:
Store in a cool and dry place away from sunlight
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
📦Pricing Information, Availability:
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